Polyphenol analysis


Polyphenol analysis


Benefits of Polyphenols analysis
 
  • Accurate and Sensitive Analysis: Provides reliable quantification of polyphenols, which is crucial for understanding their health benefits.
  • Diverse Applications: Supports research across various industries, including food, pharmaceuticals, and human health.
  • Advanced Technology: Utilizes our state-of-the-art equipment which provides maximum sensitivity, precise identification and quantification.
  • Comprehensive Analysis: We can identify and quantify a wide range of polyphenols from different sources.
  • Support for Health Research: Aids in studying the role of polyphenols in preventing diseases associated with oxidative stress.
  • Product Development and Quality Control: Assists in the development and quality assurance of food products, supplements, and extracts containing polyphenols.
Bioanalysis Services: Polyphenols
 
At QIB Extra, we provide advanced bioanalysis services designed to support your research and product development goals. Our state-of-the-art facilities and expertise enable us to offer precise and reliable analysis of polyphenols.

What are Polyphenols?
 
Polyphenols, a subgroup of phytochemical, are a varied group of naturally occurring compounds found in plants, including fruits, vegetables, tea, coffee, and red wine. Renowned for their antioxidant properties, they have been associated with various health advantages, such as alleviating inflammation, shielding against heart disease, and potentially reducing the risk of certain cancers. Polyphenols are identified by their chemical structure containing numerous phenol rings and contribute to the vivid colours of many plant-based foods.
 

How Polyphenol Analysis Can Benefit You

QIB Extra offers expert polyphenol analysis, focusing on identifying polyphenols in food samples through direct analysis and metabolite examination.

We tailor sample processing techniques, such as extraction and filtering, to effectively release and purify target compounds. Our precise chromatographic analysis and mass spectral scans allow us to identify molecular structures and fragments accurately, using advanced workflows to detect subtle differences between samples.

For targeted analysis, we detect molecules at extremely low levels, ensuring accurate results. A pre-consultation with QIB Extra helps define your sample characteristics and specific target compounds for optimal analysis.

Types of Polyphenol Analysis

  • Qualitative Analysis: Identifies polyphenols in a sample using advanced chromatographic and mass spectrometry techniques.
  • Quantitative Analysis: Measures specific polyphenol concentrations, essential for evaluating the content in foods, supplements, or extracts.
  • Total Polyphenol Content (TPC) Assays: Provides an overall view of a sample's polyphenolic composition, useful for comparing food sources or processing impacts.
  • Targeted Analysis: Focuses on specific polyphenol classes, aiding in bioavailability studies and disease prevention research.
  • Metabolite Profiling: Identifies and quantifies metabolites from polyphenol-rich foods, offering insights into bioavailability and health effects.
  • Bioactivity Assays: Assesses the biological effects of polyphenols, such as antioxidant and anti-inflammatory activities.

Our services support researchers, food manufacturers, and healthcare professionals in understanding polyphenols' role in health and disease, delivering accurate and actionable data to meet specific objectives.

Understanding Different Types of Polyphenols

To maximise the insights from our polyphenol analysis services, it's important to understand the specific polyphenols we analyse. Each class of polyphenols offers unique properties and potential health benefits. Below, we outline the most common polyphenols we examine, helping you determine which compounds are most relevant to your research or product development needs. 

Flavonoids:
These include subclasses like flavonols, flavones, flavanones, flavanols, isoflavones, and anthocyanins. They are known for their antioxidant properties and reducing inflammation and supporting cardiovascular health.
 
  • Application: Fruits (apples, berries, citrus, grapes), vegetables (onions, kale, broccoli), tea (green and black), wine (red).
Phenolic Acids:
This group includes hydroxybenzoic and hydroxycinnamic acids, known for their antioxidant, anti-inflammatory, antimicrobial properties, and their role in supporting cardiovascular and metabolic health.
 
  • Application: Coffee, fruits (apples, berries, citrus), whole grains (wheat, oats, rice).
Polyphenolic Amides:
These compounds, such as capsaicinoids in chili peppers and avenanthramides in oats, are recognised for their anti-inflammatory and potential cardiovascular benefits.
 
  • Application: Peppers, oats, potatoes, buckwheat, mustard, cocoa, and paprika.
Lignans:
Found in seeds, particularly flaxseeds, as well as in whole grains and vegetables, lignans are associated with hormone-related health benefits and may have anti-cancer properties.
 
  • Application: Seeds (flaxseeds), whole grains (rye, barley, oats), vegetables (broccoli, kale, carrots).
Stilbenes:
Resveratrol is the most well-known stilbene, primarily found in grapes, red wine, and some berries. It is noted for its potential anti-aging and cardiovascular health benefits.
 
  • Application: Grapes (especially skins), wine (red), berries (blueberries, cranberries).
Tannins:
Present in tea, coffee, wine, and certain fruits, tannins are astringent compounds that contribute to the taste and potential health benefits, including antioxidant and antimicrobial effects.
 
  • Application: Tea (black, green), coffee, wine (red), fruits (pomegranates, grapes, persimmons).
 

To learn more about our services or to discuss your specific requirements, please contact us.

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Bespoke Scientific Research

Including food science and innovation, gut health (inc. microbiome) and microbes in the food chain.

Facilities and Equipment

The Quadram Institute building contains a range of state-of-the-art facilities and equipment, including a clinical research facility and Level 3 laboratory (CL3). 

Clostridium botulinum challenge testing

QIB Extra tests for toxin types B and E as these are the common toxins associated with chilled food products however tests for other botulinum toxins are also available.

Pathogen Challenge Testing

Our pathogen food challenge testing services to evaluate the effectiveness of your food safety protocols by introducing targeted pathogens, helping you ensure your products meet the highest safety standards.

Bioanalysis Service (SCFA, LCFA, BA)

Specialising in analysis that supports our research around food innovation, gut health and food safety, our cutting-edge methods ensure accurate identification and quantification of key markers and metabolites.

DNA Sequencing

Our DNA sequencing service utilises Short- and Long-Read technologies for comprehensive genomic analysis, offering expert guidance in experimental design, data interpretation, and strategic planning.

TraDIS-Xpress

TraDIS-Xpress is a high-resolution, whole-genome assay that identifies novel mechanisms of triclosan action and resistance.

Nutritional Information Solutions (NIS)

Nutritional Information Solutions provides a cost effective service to calculate front and back of pack food labelling for food producers.  

Microscopy Services

Our microscopy services cater to diverse biomedical and food research needs. Access cutting-edge equipment, personalised training, and comprehensive support for image acquisition, processing, and analysis.

National Collection of Yeast Cultures (NCYC)

National Collection of Yeast Cultures (NCYC) provides a range of yeast related services for the brewing and baking industry and academic researchers. 

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